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Challenges and Opportunities for Overcoming Dog Use in Agrochemical Evaluation and Registration
October 25th, 2021 10 am - 1 pm EDT

The 90-day dog study is being conducted for agrochemical authorization when it is not always needed to adequately address hazard identification and human safety and risk. This virtual workshop will host a series of presentations on the role the dog study has played in regulation of agrochemicals in both the U.S. and Europe during the past 20 years and what approaches may be employed to substantially reduce its use. The public will have the opportunity to submit comments and questions to be discussed during the following invitation-only workshop.

10 am - Open remarks – Andrea Terron (EFSA) and Anna Lowit (EPA)
10:30 am – 11:50 am Pre-recorded presentations 20 minutes

Title: The value of the 90-day dog study in pesticide registration toxicity testing in the U.S.
Authors: Patricia L. Bishop (The Humane Society of the United States), Douglas C. Wolf (Syngenta Crop Protection), and Vicki Dellarco (Independent Consultant)

Title: Incorporating toxicokinetic and toxicity data to evaluate the value added from using dogs in subchronic toxicity testing for agrochemicals
Authors: Lynea Murphy (Corteva AgriScience), Robert Mingoia (Corteva AgriScience), Jean Domoradzki (Corteva AgriScience) Claire Terry (Corteva AgriScience)

Title: Relevance of dog studies for the derivation of health-based guidance values for Plant Protection Products Approval - EFSA
Authors: Martina Panzarea (EFSA) and Andrea Terron (EFSA)

Title: Origins, History, Utility, and Future of Canine Bioassays in Pharmaceuticals R&D
Author: Lewis Kinter (GLP Scientific Consulting)

Title: Species Liver-Chip to assess cross-species drug toxicity and human relevance.
Author: Kyung-Jin Jang (Emulate)

11:50 am – 12:30 pm Q&A – Cecilia Tan (EPA)
12:30 pm – 1 pm Closing remarks – Doug Wolf (Syngenta)

Oct 25, 2021 09:00 AM in Eastern Time (US and Canada)

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